SOP FOR CLEANING AND MAINTENANCE OF LAMINAR AIR FLOW

I           PURPOSE

          To describe the procedure for cleaning and maintenance of Laminar air flow.

II         SCOPE

             This procedure is applicable to Quality Control department-Penicillins.

 

III.       RESPONSIBILITY

Microbiologist – Quality Control

IV.       ACCOUNTABILITY

Incharge  - Quality Control

V       PROCEDURE

1.0              Cleaning of laminar air flow (LAF) -daily

            2.0       Clean the UV lights, tube light and manometer with sterile mop.

            3.0       Clean the working table, top and side glass with  filtered 70%  isopropyl alcohol on the grill of                     laminar flow.

            4.0       After cleaning, keep the UV lights “ON” when laminar flow is not in operation.

            5.0       Manometer reading is between 8.0 and 14.0 mm .in ‘ON’ condition and zero in ‘OFF’ condition.

            6.0       Maintain a register F01 to record positive pressures, contents are as per Table-1.

            7.0       Record the cleaning details in register F02 and the contents are as per Table-2.

            8.0       If manometers reading are out of the limit, inform maintenance department for cleaning of filters.

                             Table-1(F01/SOP PMB 004)

Title:  MANOMETER USAGE REGISTER

	COLUMN No.	NAME OF THE COLUMN			SHORT FORM		COLUMN   WIDTH(cm)
LAF-701
1		SERIAL NUMBER				----	1.5
2		DATE				----	1.5
3		SWITCHED ON/OFF		FROM		----	1.5
				TO			1.5
4		MANOMETER RANGE				----	3.0
LAF-702
1		SWITCHED ON/OFF	FROM			----	1.5
			TO				1.5
2		MANOMETER RANGE				----	3.0
3		CHECKED BY				----	2.0
4		REMARKS				----	LEFT OVER SPACE

                           Table-2 (F02/SOP PMB 004)

Title: LAF CLEANING REGISTER

	COLUMN No.	NAME OF THE COLUMN	SHORT FORM	COLUMN WIDTH(cm)
	LAF –701
1		SERIAL NUMBER	----	1.5
2		CLEANED ON	----	1.5
3		CLEANED BY	----	3.0
LAF –702
1		CLEANED ON	----	1.5
2		CLEANED BY	----	3.0
3		CHECKED BY	----	3.0
4		REMARKS	----	LEFT OVER SPACE

VI   LIST OF  FORMATS

FORMAT NUMBER	PURPOSE
F01/SOP PMB 004	MANOMETER USAGE REGISTER
F02/SOP PMB 004	LAF CLEANING REGISTER

           

VII      REASON FOR REVIEW

                      Periodic review

VIII      REVISION SUMMARY

Version No.	Revised on	Reason for Revision
02	NA	NA

END OF THE DOCUMENT